Pub. Date : 2021 May
PMID : 32108308
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, due to extensive peripheral metabolism by aromatic L-amino acid decarboxylase and catechol-O-methyltransferase (COMT), only a fraction of the levodopa dose reaches the brain unchanged. | Levodopa | catechol-O-methyltransferase | Homo sapiens |
2 | However, due to extensive peripheral metabolism by aromatic L-amino acid decarboxylase and catechol-O-methyltransferase (COMT), only a fraction of the levodopa dose reaches the brain unchanged. | Levodopa | catechol-O-methyltransferase | Homo sapiens |
3 | Thus, by preventing levodopa metabolism and increasing the availability of levodopa for uptake into the brain, the inhibition of COMT would be beneficial in Parkinson"s disease. | Levodopa | catechol-O-methyltransferase | Homo sapiens |
4 | Thus, by preventing levodopa metabolism and increasing the availability of levodopa for uptake into the brain, the inhibition of COMT would be beneficial in Parkinson"s disease. | Levodopa | catechol-O-methyltransferase | Homo sapiens |