Pub. Date : 2020 May
PMID : 32097729
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Down-regulation of intracellular ROS attenuated apoptosis and autophagy of TSCC cisplatin-resistant CAL27/CDDP cells by reversing the inhibition of p38MAPK/mTOR pathway. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | Taken together, these findings suggest that down-regulation of intracellular ROS reduces the cytotoxicity of cisplatin by inhibiting apoptosis and autophagy in TSCC cells involving p38MAPK/mTOR mediated pathway. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |