Title : Therapeutic potential of targeting SHP2 in human developmental disorders and cancers.

Pub. Date : 2020 Mar 15

PMID : 32061959






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Src homology 2 (SH2)-containing protein tyrosine phosphatase 2 (SHP2), encoded by PTPN11, regulates cell proliferation, differentiation, apoptosis and survival via releasing intramolecular autoinhibition and modulating various signaling pathways, such as mitogen-activated protein kinase (MAPK) pathway. Tyrosine protein tyrosine phosphatase non-receptor type 11 Homo sapiens
2 Src homology 2 (SH2)-containing protein tyrosine phosphatase 2 (SHP2), encoded by PTPN11, regulates cell proliferation, differentiation, apoptosis and survival via releasing intramolecular autoinhibition and modulating various signaling pathways, such as mitogen-activated protein kinase (MAPK) pathway. Tyrosine protein tyrosine phosphatase non-receptor type 11 Homo sapiens