Pub. Date : 2020 May 15
PMID : 32061854
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterization of Cu2+ and Zn2+ binding sites in SUMO1 and its impact on protein stability. | Zinc | small ubiquitin like modifier 1 | Homo sapiens |
| 2 | Between Cu2+ and Zn2+, the former binds more strongly with SUMO1 as determined using fluorescence spectroscopy. | Zinc | small ubiquitin like modifier 1 | Homo sapiens |
| 3 | Cu2+ induced paramagnetic quenching and Zn2+ induced chemical shift perturbation of 15N-1H cross-peaks were used to identify their respective binding sites in SUMO1. | Zinc | small ubiquitin like modifier 1 | Homo sapiens |
| 4 | Our findings provide structural insights into the SUMO1-Cu2+/Zn2+ interaction, and its impact on aggregation of SUMO1 which might affect its ability to modify functions of target proteins. | Zinc | small ubiquitin like modifier 1 | Homo sapiens |