Protein Name | small ubiquitin like modifier 1 |
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Organism | Homo sapiens |
Gene ID | 7341 |
Gene Symbol | SUMO1 |
UniProt | P63165 (SUMO1_HUMAN), A0A024R3Z2 (A0A024R3Z2_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
168
Total Number of Articles : 256 |
Description |
small ubiquitin like modifier 1 |
Gene Summary |
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |