Protein Name small ubiquitin like modifier 1
Organism Homo sapiens
Gene ID 7341
Gene Symbol

SUMO1

UniProt P63165 (SUMO1_HUMAN), A0A024R3Z2 (A0A024R3Z2_HUMAN)
Relationships Total Number of functionally related compound(s) : 168
Total Number of Articles : 256
Description

small ubiquitin like modifier 1

Gene Summary

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

synonyms
  • small ubiquitin-related modifier 1
  • GAP modifying protein 1
  • SMT3 homolog 3
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Properties