Title : Restoration of MARCKS enhances chemosensitivity in cancer.

Pub. Date : 2020 Apr

PMID : 32056006






2 Functional Relationships(s)
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Protein Name
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1 In CRC cells, bosutinib treatment resulted in a MARCKS translocation from the cytosol to the plasma membrane, while simultaneously, ABCB1 was relocated to intracellular compartments. bosutinib myristoylated alanine rich protein kinase C substrate Homo sapiens
2 Inhibition of MARCKS phosphorylation via bosutinib rendered cells more sensitive to the chemotherapeutics doxorubicin and 5-FU. bosutinib myristoylated alanine rich protein kinase C substrate Homo sapiens