Title : Low-dose microcystin-LR antagonizes aflatoxin B1 induced hepatocarcinogenesis through decreasing cytochrome P450 1A2 expression and aflatoxin B1-DNA adduct generation.

Pub. Date : 2020 Jun

PMID : 32045972






1 Functional Relationships(s)
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1 These results suggest that when co-exposure with AFB1, MC-LR might repress hepatocarcinogenicity of AFB1, which might be associated with its repression on AFB1 induced CYP1A2 upregulation and activation. Aflatoxin B1 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus