Title : Inhibited Nitric Oxide Production of Human Endothelial Nitric Oxide Synthase by Nitrated and Oxygenated Polycyclic Aromatic Hydrocarbons.

Pub. Date : 2020 Mar 3

PMID : 32022550






1 Functional Relationships(s)
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1 The eNOS enzymatic activity and NO production were promoted by NAP, ANT and FLU, however, eNOS activity was dropped by 52.8%, 52.1%, 52.5% and 44.5% and NO production was decreased by 31.1%, 50.3%, 65.0% and 35.0% after 24 h exposure to 0.01 microM 1-NNAP, 9-NANT, 9,10-AQ and 9-FLU, respectively. N-(2-naphthalenesulfonyl)aspartyl-(2-phenethyl)amide nitric oxide synthase 3 Homo sapiens