Pub. Date : 2020 Apr
PMID : 32015510
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It has also been found to be over-expressed in AML patients, with activating mutations in foetal liver tyrosine kinase 3 (FLT3), particularly those with internal tandem duplications (FLT3-ITD), where it transactivates FLT3-ITD and confers resistance to treatment with FLT3 tyrosine kinase inhibitors (TKIs). | Tyrosine | fms related receptor tyrosine kinase 3 | Homo sapiens |
| 2 | It has also been found to be over-expressed in AML patients, with activating mutations in foetal liver tyrosine kinase 3 (FLT3), particularly those with internal tandem duplications (FLT3-ITD), where it transactivates FLT3-ITD and confers resistance to treatment with FLT3 tyrosine kinase inhibitors (TKIs). | Tyrosine | fms related receptor tyrosine kinase 3 | Homo sapiens |
| 3 | It has also been found to be over-expressed in AML patients, with activating mutations in foetal liver tyrosine kinase 3 (FLT3), particularly those with internal tandem duplications (FLT3-ITD), where it transactivates FLT3-ITD and confers resistance to treatment with FLT3 tyrosine kinase inhibitors (TKIs). | Tyrosine | fms related receptor tyrosine kinase 3 | Homo sapiens |
| 4 | It has also been found to be over-expressed in AML patients, with activating mutations in foetal liver tyrosine kinase 3 (FLT3), particularly those with internal tandem duplications (FLT3-ITD), where it transactivates FLT3-ITD and confers resistance to treatment with FLT3 tyrosine kinase inhibitors (TKIs). | Tyrosine | fms related receptor tyrosine kinase 3 | Homo sapiens |