Pub. Date : 2020 Feb
PMID : 32010314
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The protein content of NLRP3, ASC, Casp-1, IL-1beta and IL-18 in the aorta in ApoE-/- mice was remarkably increased, and they were inhibited to some extent after tacrolimus intervention. | Tacrolimus | interleukin 1 alpha | Mus musculus |
| 2 | In conclusion, it is speculated that tacrolimus may reduce the formation of AS through inhibiting ROS in macrophages and activation of NLRP3 inflammatory corpuscles and reducing the release of IL-1beta and IL-18. | Tacrolimus | interleukin 1 alpha | Mus musculus |