Title : The effect of naproxen patches on relieving orthodontic pain by evaluation of VAS and IL-1β inflammatory factor: a split-mouth study.

Pub. Date : 2019 Nov-Dec

PMID : 31994643






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1 The effect of naproxen patches on relieving orthodontic pain by evaluation of VAS and IL-1beta inflammatory factor: a split-mouth study. Naproxen interleukin 1 alpha Homo sapiens
2 Objective: The present study aimed to compare the efficacy of naproxen patches in pain control during orthodontic tooth separation, by means of visual analogue scale (VAS) and interleukin 1beta (IL-1beta) levels in gingival crevicular fluid (GCF). Naproxen interleukin 1 alpha Homo sapiens
3 Significant differences were found in pain scores (p< 0.0001) and IL-1beta levels (p= 0.047) between naproxen and placebo groups. Naproxen interleukin 1 alpha Homo sapiens
4 IL-1beta levels were lower for the patients using naproxen patches only 1 hour after separation (p= 0.047). Naproxen interleukin 1 alpha Homo sapiens
5 CONCLUSION: In the light of VAS scores and IL-1beta levels, naproxen patches reduced the pain caused by separator placement. Naproxen interleukin 1 alpha Homo sapiens