Title : Ultrasound Assisted Synthesis of 2-Substituted Benzofurans via One-Pot and Sequential Method: Their In Vitro Evaluation.

Pub. Date : 2020

PMID : 31994471






3 Functional Relationships(s)
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1 RESULTS: The benzofuran derivative 3m showed encouraging growth inhibition of both MDAMB-231 and MCF-7 cell lines and significant inhibition of SIRT1. benzofuran sirtuin 1 Homo sapiens
2 CONCLUSION: Our efforts not only accomplished a one-pot and direct access to 2-(het)aryl substituted benzofurans but also revealed that the benzofuran framework presented here could be a potential template for the identification of potent inhibitors of SIRT1. benzofuran sirtuin 1 Homo sapiens
3 CONCLUSION: Our efforts not only accomplished a one-pot and direct access to 2-(het)aryl substituted benzofurans but also revealed that the benzofuran framework presented here could be a potential template for the identification of potent inhibitors of SIRT1. benzofuran sirtuin 1 Homo sapiens