Title : Luteolin prevents irinotecan-induced intestinal mucositis in mice through antioxidant and anti-inflammatory properties.

Pub. Date : 2020 May

PMID : 31976547






1 Functional Relationships(s)
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1 Moreover, luteolin treatment mitigated irinotecan-induced oxidative stress (i.e. by reducing the levels of ROS and LOOH, and augmenting endogenous antioxidants) and inflammation (i.e. through the decrease of MPO enzyme activity, TNF, IL-1beta, and IL-6 levels; and increasing IL-4 and IL-10). Luteolin tumor necrosis factor Mus musculus