Title : Novel Peptide CM 7 Targeted c-Met with Antitumor Activity.

Pub. Date : 2020 Jan 21

PMID : 31973231






3 Functional Relationships(s)
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1 Anomalous changes of the cell mesenchymal-epithelial transition factor (c-Met) receptor tyrosine kinase signaling pathway play an important role in the occurrence and development of human cancers, including gastric cancer. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens
2 Anomalous changes of the cell mesenchymal-epithelial transition factor (c-Met) receptor tyrosine kinase signaling pathway play an important role in the occurrence and development of human cancers, including gastric cancer. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens
3 In this study, we designed and synthesized a novel peptide (CM 7) targeting the tyrosine kinase receptor c-Met, that can inhibit c-Met-mediated signaling in MKN-45 and U87 cells. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens