Title : Reduced release of TNF and PCA from macrophages of tolerant mice.

Pub. Date : 1988 Oct

PMID : 3197264






1 Functional Relationships(s)
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1 A regulatory mechanism of E-series prostaglandins (PGE) might be involved in the induction of hyporesponsiveness in macrophages of tolerant mice, as the LPS-stimulated TNF release could be inhibited in a dose dependent manner by preincubation with PGE1. Prostaglandins tumor necrosis factor Mus musculus