Title : Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice.

Pub. Date : 2020 Dec

PMID : 31967706






1 Functional Relationships(s)
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Protein Name
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1 Irb suppressed APAP-caused elevation of liver enzymes as well as oxidative and nitrosative stress in liver tissues as evidenced by the decrease in hepatic CYP2E1 expression and hepatic levels of malondialdehyde and nitric oxide in addition to the elevated hepatic superoxide dismutase activity and reduced glutathione concentration. Acetaminophen cytochrome P450, family 2, subfamily e, polypeptide 1 Mus musculus