Pub. Date : 2017
PMID : 31966806
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cisplatin inhibits the growth, migration and invasion of cervical cancer cells by down-regulating IL-17E/IL-17RB. | Cisplatin | interleukin 25 | Homo sapiens |
| 2 | The present study was performed to investigate whether cisplatin regulates the expression of IL-17E and it receptor IL-17RB, and the role of IL17E in cervical cancer cells in vitro. | Cisplatin | interleukin 25 | Homo sapiens |
| 3 | Cisplatin significantly down-regulated the expression of IL-17E and IL-17RB, and further reversed the regulatory effects of rhIL-17E on viability, apoptosis, migration and invasion of HeLa and SiHa cells. | Cisplatin | interleukin 25 | Homo sapiens |
| 4 | The results suggest that cisplatin inhibits the viability, migration, invasion, and promotes the apoptosis of cervical cancer cells possibly by down-regulating IL-17E/17RB signaling. | Cisplatin | interleukin 25 | Homo sapiens |
| 5 | Cisplatin may be the first choice for cervical cancer patients with abnormally high IL-17E expression. | Cisplatin | interleukin 25 | Homo sapiens |