Pub. Date : 2020 Apr
PMID : 31954876
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The activation of PI3K/Akt/mTOR signaling pathway was significantly suppressed by prazosin via reducing the phosphorylation of Akt and mTOR. | Prazosin | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | The activation of PI3K/Akt/mTOR signaling pathway was significantly suppressed by prazosin via reducing the phosphorylation of Akt and mTOR. | Prazosin | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | CONCLUSION: These results highlight an anti-cancer activity of prazosin on AML by inhibiting the PI3K/Akt/mTOR pathway and targeting TNS1. | Prazosin | mechanistic target of rapamycin kinase | Homo sapiens |