Title : Pregnenolonyl-α-glucoside exhibits marked anti-cancer and CYP17A1 enzymatic inhibitory activities.

Pub. Date : 2020 Feb 6

PMID : 31938799






2 Functional Relationships(s)
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1 An in vitro CYP17A1 binding pattern assay and protein-ligand docking model support that 2, like abiraterone, binds in the active site heme iron pocket of CYP17A1. Iron cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 An in vitro CYP17A1 binding pattern assay and protein-ligand docking model support that 2, like abiraterone, binds in the active site heme iron pocket of CYP17A1. Iron cytochrome P450 family 17 subfamily A member 1 Homo sapiens