Title : Treatment of human skeletal muscle cells with inhibitors of diacylglycerol acyltransferases 1 and 2 to explore isozyme-specific roles on lipid metabolism.

Pub. Date : 2020 Jan 14

PMID : 31937853






3 Functional Relationships(s)
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Protein Name
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1 The results showed that DGAT1 was dominant in human skeletal muscle cells utilizing fatty acids (FAs) derived from various sources, both exogenously supplied FA, de novo synthesised FA, or FA derived from lipolysis, to generate TAG, as well as being involved in de novo synthesis of TAG. Fatty Acids diacylglycerol O-acyltransferase 1 Homo sapiens
2 The results showed that DGAT1 was dominant in human skeletal muscle cells utilizing fatty acids (FAs) derived from various sources, both exogenously supplied FA, de novo synthesised FA, or FA derived from lipolysis, to generate TAG, as well as being involved in de novo synthesis of TAG. Fatty Acids diacylglycerol O-acyltransferase 1 Homo sapiens
3 Interestingly, DGAT activities were also important for regulating FA oxidation, indicating a key role in balancing FAs between storage in TAG and efficient utilization through oxidation. Fatty Acids diacylglycerol O-acyltransferase 1 Homo sapiens