Title : Abnormality of intestinal cholesterol absorption in ApcMin/+ mice with colon cancer cachexia.

Pub. Date : 2019

PMID : 31933883






2 Functional Relationships(s)
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1 We found that both triglyceride (TG) and total cholesterol (TC) uptake were inhibited in the intestine of ApcMin/+ mice with age and the intestinal peroxisome proliferator-activated receptor alpha (PPARalpha) downregulated the processes of beta-oxidation, oxidative stress response, and cholesterol absorption in APC-deficient mice. Cholesterol peroxisome proliferator activated receptor alpha Mus musculus
2 We found that both triglyceride (TG) and total cholesterol (TC) uptake were inhibited in the intestine of ApcMin/+ mice with age and the intestinal peroxisome proliferator-activated receptor alpha (PPARalpha) downregulated the processes of beta-oxidation, oxidative stress response, and cholesterol absorption in APC-deficient mice. Cholesterol peroxisome proliferator activated receptor alpha Mus musculus