Title : 6-Ketocholestanol suppresses lipid accumulation by decreasing FASN gene expression through SREBP-dependent regulation in HepG2 cells.

Pub. Date : 2020 Feb

PMID : 31933103






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Similar to 6-keto, 6alpha-OH and 6beta-OH significantly reduced the activity of the FASN gene promoter, which suggests that oxidation of carbon-6 in the B-ring may play an important role in the reduction of FASN expression. Carbon fatty acid synthase Homo sapiens
2 Similar to 6-keto, 6alpha-OH and 6beta-OH significantly reduced the activity of the FASN gene promoter, which suggests that oxidation of carbon-6 in the B-ring may play an important role in the reduction of FASN expression. Carbon fatty acid synthase Homo sapiens