Title : Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.

Pub. Date : 2020 Feb

PMID : 31930778






1 Functional Relationships(s)
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1 Additionally, AOAA attenuated NLRP3-Caspase1/IL-1beta activation and decreased the release of IL-6 and TNF-alpha pro-inflammatory cytokines and reciprocally increased IL-10 anti-inflammatory cytokine level in both ischaemic myocardium and M1 macrophages. Aminooxyacetic Acid interleukin 10 Mus musculus