Pub. Date : 2020 Feb 3
PMID : 31929192
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Polymorphisms in the endoplasmic reticular protein orosomucoid-like protein 3 (ORMDL3), which regulates sphingolipid homeostasis, have been strongly linked with childhood-onset asthma. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |
| 2 | Despite extensive investigation, a link between ORMDL3 asthma-risk genotypes and altered sphingolipid synthesis has been lacking. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |
| 3 | These results demonstrate that genetic variants in ORMDL3 may confer a risk of developing childhood asthma through dysregulation of sphingolipid synthesis. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |