Title : Angiotensin II Type I Receptor Antagonism Attenuates Nicotine-Induced Cardiac Remodeling, Dysfunction, and Aggravation of Myocardial Ischemia-Reperfusion Injury in Rats.

Pub. Date : 2019

PMID : 31920673






3 Functional Relationships(s)
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1 This study sought to elucidate the role of angiotensin II type I (AT1) receptors in cardiac injury resulting from prolonged nicotine administration in a rat model. Nicotine angiotensin II receptor, type 1a Rattus norvegicus
2 These findings suggest that AT1 receptors play an important role in nicotine-induced cardiac dysfunction, and pharmacological approaches targeting cardiac AT1 receptors may thus benefit patients with sustained exposure to nicotine. Nicotine angiotensin II receptor, type 1a Rattus norvegicus
3 These findings suggest that AT1 receptors play an important role in nicotine-induced cardiac dysfunction, and pharmacological approaches targeting cardiac AT1 receptors may thus benefit patients with sustained exposure to nicotine. Nicotine angiotensin II receptor, type 1a Rattus norvegicus