Pub. Date : 2020 Mar
PMID : 31917466
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Propafenone analogue with additional H-bond acceptor group shows increased inhibitory activity on P-glycoprotein. | Propafenone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | In a previous work, it has been shown that propafenone analogs with a 4-hydroxy-4-piperidine moiety exhibit a generally 10-fold higher P-gp inhibitory activity than expected based on their lipophilicity. | Propafenone | ATP binding cassette subfamily B member 1 | Homo sapiens |