Title : Interplay of adenosine monophosphate-activated protein kinase/sirtuin-1 activation and sodium influx inhibition mediates the renal benefits of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes: A novel conceptual framework.

Pub. Date : 2020 May

PMID : 31916329






1 Functional Relationships(s)
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1 Enhanced AMPK/SIRT1 signaling may also contribute to the action of SGLT2 inhibitors to interfere with sodium transport mechanisms. Sodium protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens