Title : New pyrazole derivatives possessing amino/methanesulphonyl pharmacophore with good gastric safety profile: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory activity and histopathological studies.

Pub. Date : 2020 Jan

PMID : 31911297






1 Functional Relationships(s)
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1 New series of pyrazole derivatives Va-c, VIa-c, VIIa-f, and VIII possessing amino/methanesulphonyl moiety as COX-2 pharmacophore were designed and synthesized. Amino Acids cytochrome c oxidase subunit 8A Homo sapiens