Title : Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18.

Pub. Date : 2020 Feb

PMID : 31907993






1 Functional Relationships(s)
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1 Importantly, we show that selective targeting of glycans on CD11b with such lectins results in altered intracellular signaling events that inhibit TEpM and differentially affect key PMN inflammatory functions including phagocytosis, superoxide release and apoptosis. Superoxides integrin subunit alpha M Homo sapiens