Title : Crizotinib-induced osteitis mimicking bone metastasis in a stage IV ALK-rearranged NSCLC patient: a case report.

Pub. Date : 2020 Jan 6

PMID : 31906956






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Crizotinib-induced osteitis mimicking bone metastasis in a stage IV ALK-rearranged NSCLC patient: a case report. crizotinib ALK receptor tyrosine kinase Homo sapiens
2 Here, we report a case of osteitis induced by an ALK inhibitor mimicking bone metastasis, a previously undescribed side effect of crizotinib. crizotinib ALK receptor tyrosine kinase Homo sapiens
3 CASE PRESENTATION: A 31-year-old woman with stage IV ALK-rearranged NSCLC presented with back pain after 3 months of crizotinib treatment. crizotinib ALK receptor tyrosine kinase Homo sapiens
4 Crizotinib differs from other ALK inhibitors as it targets other kinases as well, which may have been responsible for the osteitis. crizotinib ALK receptor tyrosine kinase Homo sapiens