Title : Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy.

Pub. Date : 2019 Dec 31

PMID : 31906147






1 Functional Relationships(s)
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1 In neurons, celastrol enhances autophagy, autophagosome biogenesis (Beclin 1 , Ambra1 , Vps34 , Atg7 , Atg12 , and LC3-II ), and mitophagy (PINK1 , DJ-1 , and LRRK2 ), and these might be associated with MPAK signaling pathways. celastrol leucine-rich repeat kinase 2 Mus musculus