Title : Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells.

Pub. Date : 2019 Dec 30

PMID : 31905925






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We also showed that (1) the AUR-induced GDNF production was inhibited by U0126, a specific inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) 1/2, and by H89, a specific inhibitor of protein kinase A (PKA); and (2) AUR induced the phosphorylation of cAMP response element-binding protein (CREB), a transcription factor located within the nucleus. N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus
2 We also showed that (1) the AUR-induced GDNF production was inhibited by U0126, a specific inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) 1/2, and by H89, a specific inhibitor of protein kinase A (PKA); and (2) AUR induced the phosphorylation of cAMP response element-binding protein (CREB), a transcription factor located within the nucleus. N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus