CPRiL

Prkaca

protein kinase cAMP-activated catalytic subunit alpha

Enables cAMP-dependent protein kinase activity; protein kinase binding activity; and small GTPase binding activity. Involved in several processes, including circadian sleep/wake cycle, REM sleep; regulation of glutamatergic synaptic transmission; and spontaneous exocytosis of neurotransmitter. Located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and presynapse. Part of cAMP-dependent protein kinase complex. Biomarker of brain ischemia. Human ortholog(s) of this gene implicated in adrenal cortical adenoma; congestive heart failure; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKACA (protein kinase cAMP-activated catalytic subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

• cAMP-dependent protein kinase catalytic subunit alpha
• PKA C-alpha
• cAMP-dependent protein kinase catalytic subunit C alpha
protein kinase A
protein kinase, cAMP-dependent, alpha catalytic subunit
protein kinase, cAMP-dependent, catalytic, alpha
Cs-PKA
PKCA1