Title : Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway.

Pub. Date : 2020 Jun

PMID : 31904145






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Western blot analysis results revealed that the Hh/Gli pathway was activated in cisplatin-resistant A2780/DDP cells. Cisplatin GLI family zinc finger 1 Homo sapiens
2 All results showed that inhibiting Hh/Gli signaling may negatively regulate the proliferation, invasion, and metastasis of cisplatin-resistant A2780/DDP cells, as well as increase the sensitivity of A2780/DDP to the chemotherapeutic drug of cisplatin. Cisplatin GLI family zinc finger 1 Homo sapiens
3 All results showed that inhibiting Hh/Gli signaling may negatively regulate the proliferation, invasion, and metastasis of cisplatin-resistant A2780/DDP cells, as well as increase the sensitivity of A2780/DDP to the chemotherapeutic drug of cisplatin. Cisplatin GLI family zinc finger 1 Homo sapiens