Title : Altered DNA methylation of TRIM13 in diabetic nephropathy suppresses mesangial collagen synthesis by promoting ubiquitination of CHOP.

Pub. Date : 2020 Jan

PMID : 31901873






1 Functional Relationships(s)
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1 METHODS: The differential expression of CHOP and TRIM13 which is a well-defined E3 ubiquitin ligase was compared in renal biopsy samples from DN/normal renal tissues, in isolated glomeruli of diabetic/control mice, as well as in high glucose (HG) or TGF-beta1-stimulated renal mesangial cells. Glucose DNA-damage inducible transcript 3 Mus musculus