Title : Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1.

Pub. Date : 2020

PMID : 31897243






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1. Metformin Yes1 associated transcriptional regulator Homo sapiens
2 In addition, we found that the combination of metformin and LW6 increased the phosphorylation of yes-associated protein 1 at serine 127 and attenuated the nuclear localization of this transcription factor. Metformin Yes1 associated transcriptional regulator Homo sapiens
3 This suggests that metformin in combination with LW6 impairs pancreatic cancer cells and reduces nuclear localization of yes-associated protein 1. Metformin Yes1 associated transcriptional regulator Homo sapiens