Title : Exopolysaccharides isolated from Rhizopus nigricans induced colon cancer cell apoptosis in vitro and in vivo via activating the AMPK pathway.

Pub. Date : 2020 Jan 31

PMID : 31894839






1 Functional Relationships(s)
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1 In vivo, azoxymethane/dextran sulfate sodium (AOM/DSS)-treated CRC mice, when administered EPS1-1, exhibited activation of the AMPK pathway, inhibition of mTORC1, and accumulation of p53 in tumor tissues. Azoxymethane protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens