Title : Flow-Based Three-Dimensional Co-Culture Model for Long-Term Hepatotoxicity Prediction.

Pub. Date : 2019 Dec 27

PMID : 31892214






1 Functional Relationships(s)
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1 Additionally, an acetaminophen (AAP) and isoniazid (INH) concentration-dependent increase in CYP3A4 expression was detected in the 3-D cultures, and an increase in Lactate dehydrogenase (LDH) release after AAP and INH treatment was observed. Isoniazid cytochrome P450 family 3 subfamily A member 4 Homo sapiens