Title : Feedback Regulation of Syk by Protein Kinase C in Human Platelets.

Pub. Date : 2019 Dec 25

PMID : 31881809






3 Functional Relationships(s)
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Protein Name
Organism
1 The spleen tyrosine kinase (Syk) is essential for immunoreceptor tyrosine-based activation motif (ITAM)-dependent platelet activation, and it is stimulated by Src-family kinase (SFK)-/Syk-mediated phosphorylation of Y352 (interdomain-B) and Y525/526 (kinase domain). Tyrosine spleen associated tyrosine kinase Homo sapiens
2 The spleen tyrosine kinase (Syk) is essential for immunoreceptor tyrosine-based activation motif (ITAM)-dependent platelet activation, and it is stimulated by Src-family kinase (SFK)-/Syk-mediated phosphorylation of Y352 (interdomain-B) and Y525/526 (kinase domain). Tyrosine spleen associated tyrosine kinase Homo sapiens
3 GFX and iloprost inhibited convulxin/EB-induced Syk S297 phosphorylation but enhanced Syk tyrosine (Y352/Y525/526) and substrate (linker adaptor for T cells (LAT), phospholipase gamma2 (PLC gamma2)) phosphorylation. Tyrosine spleen associated tyrosine kinase Homo sapiens