Title : Haploidentical bone marrow transplantation in a patient with sickle cell disease and acute myeloid leukemia.

Pub. Date : 2020 Feb

PMID : 31880407






2 Functional Relationships(s)
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1 Herein, we report a 14-year-old girl of Haitian descent with sickle beta zero thalassemia on chronic hydroxyurea therapy who developed FMS-like tyrosine kinase 3 (FLT3)-mutated acute myeloid leukemia and underwent a complete disease remission following a combination chemotherapy with sorafenib and was subsequently treated using a T cell replete unmanipulated haploidentical bone marrow transplantation followed by post-transplant cyclophosphamide. sorafenib fms related receptor tyrosine kinase 3 Homo sapiens
2 Herein, we report a 14-year-old girl of Haitian descent with sickle beta zero thalassemia on chronic hydroxyurea therapy who developed FMS-like tyrosine kinase 3 (FLT3)-mutated acute myeloid leukemia and underwent a complete disease remission following a combination chemotherapy with sorafenib and was subsequently treated using a T cell replete unmanipulated haploidentical bone marrow transplantation followed by post-transplant cyclophosphamide. sorafenib fms related receptor tyrosine kinase 3 Homo sapiens