Pub. Date : 2019 Dec 24
PMID : 31878222
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Robust evidence suggests that the major mechanism driving impaired beta-cell function and insulin signalling is through the action of intracellular reactive oxygen species (ROS)-induced stress. | Oxygen | insulin | Homo sapiens |
2 | Reactive oxygen species can disrupt intracellular signalling pathways, thereby dysregulating the expression of genes associated with insulin secretion and signalling. | Oxygen | insulin | Homo sapiens |