Title : Activated clotting factor X mediates mitochondrial alterations and inflammatory responses via protease-activated receptor signaling in alveolar epithelial cells.

Pub. Date : 2020 Feb 15

PMID : 31877279






1 Functional Relationships(s)
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1 FXa activated ERK1/2 and induced an increase in the expression of pro-inflammatory cytokines, which was prevented by an inhibitor of FXa, edoxaban, or an inhibitor of protease-activated receptor 1, vorapaxar. vorapaxar mitogen-activated protein kinase 3 Homo sapiens