Title : Gadolinium-based MRI contrast agent for the detection of tyrosinase.

Pub. Date : 2020 Feb 17

PMID : 31872821






3 Functional Relationships(s)
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Protein Name
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1 Tyrosinase is a key enzyme that has long been considered as a biomarker for melanoma as it catalyzes the oxidation of tyrosine and l-DOPA in melanogenesis. Tyrosine tyrosinase Homo sapiens
2 Herein, we successfully designed and synthesized a tyrosinase-targeting Gd(iii)-based MR contrast agent Tyr-GBCA 1. Tyrosine tyrosinase Homo sapiens
3 Tyr-GBCA 1 shows a 21% increase in the T1 relaxation rate (R1) in the presence of tyrosinase in artificial cerebral spinal fluid. Tyrosine tyrosinase Homo sapiens