Title : Population pharmacokinetic analysis of intravenous busulfan: GSTA1 genotype is not a predictive factor of initial dose in Chinese adult patients undergoing hematopoietic stem cell transplantation.

Pub. Date : 2020 Feb

PMID : 31834435






1 Functional Relationships(s)
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1 PURPOSE: This study aimed to develop a population pharmacokinetic (PPK) model to investigate the impact of GSTA1, GSTP1, and GSTM1 genotypes on busulfan pharmacokinetic (PK) variability in Chinese adult patients. Busulfan glutathione S-transferase pi 1 Homo sapiens