Pub. Date : 2019 Dec 7
PMID : 31832001
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, LB100 significantly downregulated the protein levels of acetyl-CoA carboxylase, sterol regulatory element-binding protein 1 and its lipogenesis target genes, including stearoyl-CoA desaturase-1 and fatty acid synthase, and upregulated the levels of proteins involved in fatty acid beta-oxidation, such as peroxisome proliferator-activated receptor alpha (PPARalpha), peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha), carnitine palmitoyltransferase 1alpha, acyl-CoA oxidase 1 and uncoupling protein 2, as well as the upstream mediators Sirt1 and AMPKalpha in the livers of HFD-fed mice. | Fatty Acids | sterol regulatory element binding transcription factor 1 | Mus musculus |