Pub. Date : 2019 Dec 10
PMID : 31822725
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Several recent publications demonstrated that DRD2-targeting antipsychotics such as thioridazine induce proliferation arrest and apoptosis in diverse cancer cell types including those derived from brain, lung, colon, and breast. | Thioridazine | dopamine receptor D2 | Homo sapiens |
| 2 | Further, DRD2 stimulation with quinpirole, a DRD2 agonist, promotes self-renewal, even in cell lines in which thioridazine does not inhibit self-renewal. | Thioridazine | dopamine receptor D2 | Homo sapiens |