Title : Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant Prostate Cancer.

Pub. Date : 2019 Dec 3

PMID : 31816863






2 Functional Relationships(s)
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1 RESULTS: Celecoxib reduced cell growth and induced apoptosis through AKT blockade, cleavage of poly (ADP-ribose) polymerase-1 (PARP-1), and proteasomal degradation of the anti-apoptotic protein Mcl-1. celecoxib poly(ADP-ribose) polymerase 1 Homo sapiens
2 RESULTS: Celecoxib reduced cell growth and induced apoptosis through AKT blockade, cleavage of poly (ADP-ribose) polymerase-1 (PARP-1), and proteasomal degradation of the anti-apoptotic protein Mcl-1. celecoxib poly(ADP-ribose) polymerase 1 Homo sapiens