Title : Isosteroid alkaloids with different chemical structures from Fritillariae cirrhosae bulbus alleviate LPS-induced inflammatory response in RAW 264.7 cells by MAPK signaling pathway.

Pub. Date : 2020 Jan

PMID : 31816576






3 Functional Relationships(s)
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1 Treatment with the five isosteroid alkaloids in appropriate concentrations could reduce the production of nitric oxide (NO), tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) in supernatant, and suppressed the mRNA expressions of TNF-alpha and IL-6. Alkaloids tumor necrosis factor Mus musculus
2 Treatment with the five isosteroid alkaloids in appropriate concentrations could reduce the production of nitric oxide (NO), tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) in supernatant, and suppressed the mRNA expressions of TNF-alpha and IL-6. Alkaloids tumor necrosis factor Mus musculus
3 Treatment with the five isosteroid alkaloids in appropriate concentrations could reduce the production of nitric oxide (NO), tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) in supernatant, and suppressed the mRNA expressions of TNF-alpha and IL-6. Alkaloids tumor necrosis factor Mus musculus