Title : Metabolite Profiling and Reaction Phenotyping for the in Vitro Assessment of the Bioactivation of Bromfenac †.

Pub. Date : 2020 Jan 21

PMID : 31815452






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 It was determined that UGT2B7 converts bromfenac to BI, and that while CYP2C8, CYP2C9 and CYP2C19 catalyze the hydroxylation of bromfenac, only CYP2C9 forms thioether adducts when incubated with NAC or GSH as trapping agents. bromfenac synuclein alpha Homo sapiens