Title : Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.

Pub. Date : 2020 Feb

PMID : 31793679






1 Functional Relationships(s)
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1 Difluoromethylornithine (DFMO) is an ODC inhibitor, which inhibits NMBA-induced activation of p38 alpha, ERK1/2 and AKT/mTOR/p70S6K pathways; this has been verified by Western blotting. nitrosobenzylmethylamine ribosomal protein S6 kinase B1 Homo sapiens